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Science · Research-Grade Compounds 8 compounds · 1 standard

The science
behind
every vial.

Every compound we carry is verified by high-performance liquid chromatography before it ships. ≥99% purity is not a claim — it is a measurement, documented in a Certificate of Analysis attached to every order.

≥99%
HPLC purity — all compounds
100%
Third-party COA per batch
−20°C
Storage & cold-chain standard
8
Compounds in active inventory
Method HPLC
Form Lyophilized
Testing 3rd Party
Origin Miami, FL
01 · Foundation

Peptides,
defined.

Peptides are short chains of amino acids — the same building blocks as proteins, but smaller and more bioavailable. The human body produces hundreds endogenously: hormones, signaling molecules, enzyme cofactors. Research peptides are synthetic analogs of these endogenous sequences, produced with pharmaceutical-grade precision for use in controlled scientific studies.

"Research grade" is not a marketing label. It refers to a specific standard of synthesis and verification: solid-phase peptide synthesis (SPPS) followed by HPLC purification and mass spectrometry confirmation of identity and purity. Our threshold is ≥99% by area under the HPLC curve — meaning total impurities amount to less than 1% by concentration.

Synthesis
Solid-Phase
(SPPS)
Verification
HPLC +
Mass Spec
Minimum purity
≥99.0%
area
02 · Quality standard

What ≥99%
actually means.

How we verify every lot
01
Synthesis

Each compound is produced via solid-phase peptide synthesis. Sequential amino acid coupling builds the target sequence with controlled stereochemistry. Crude product then undergoes preparative HPLC to remove incomplete sequences, deletion peptides, and residual synthesis reagents.

02
HPLC Analysis

Analytical reverse-phase HPLC measures peak area percentages across a UV chromatogram. A compound reaches 99%+ only when the target peak represents ≥99% of total integrated peak area. Results are instrument-generated, not estimated. Mass spectrometry confirms molecular identity independently.

03
Certificate of Analysis

A third-party analytical laboratory issues a COA for every production batch, documenting: lot number, synthesis date, HPLC purity percentage, mass spectrometry identity confirmation, and storage conditions. Your COA is available in your account dashboard and via QR on every vial label.

Why third-party matters

In-house testing creates a conflict of interest — the same organization that sells the compound also validates it. We use an independent analytical laboratory with no financial stake in the result. Their instruments, their chromatograms, their signature on the COA.

Access COA library
03 · Compound index

8 compounds.
One standard.

Full catalog
UPC-001
GHK-Cu
Copper Tripeptide-1
99.6% HPLC
CAS
89030-95-5
MW
402.93 g/mol
Formula
C₁₄H₂₄N₆O₄ · Cu
Storage
−20°C / Lyophilized
ECM remodeling Collagen synthesis Anti-fibrotic signaling

Endogenous tripeptide that binds Cu²⁺ with high affinity. Activates fibroblasts via the TGF-β pathway and upregulates synthesis of collagen types I and III. Research demonstrates modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs), relevant to connective tissue homeostasis.

UPC-002
RTA-408
Omaveloxolone Analog
99.2% HPLC
CAS
1474034-05-3
MW
554.71 g/mol
Formula
C₃₃H₄₄F₂N₂O₃
Storage
−20°C / Lyophilized
Keap1 / Nrf2 pathway Mitochondrial function Oxidative stress

Synthetic oleanane triterpenoid that covalently modifies Keap1 cysteine residues, preventing Keap1-mediated Nrf2 ubiquitination. Released Nrf2 translocates to the nucleus and drives ARE-dependent transcription of antioxidant enzymes including HO-1, NQO1, and glutathione synthetase.

UPC-003
BPC-157
Body Protective Compound
99.4% HPLC
CAS
137525-51-0
MW
1419.5 g/mol
Formula
C₆₂H₉₈N₁₆O₂₂
Storage
−20°C / Lyophilized
Tissue repair Angiogenesis GI mucosal integrity

Fifteen-amino-acid sequence derived from human gastric juice protein BPC. Research demonstrates upregulation of VEGF and its receptor VEGFR2, supporting angiogenic activity. Modulates nitric oxide synthesis and shows affinity for the growth hormone receptor in rodent models.

UPC-004
TB-500
Thymosin β-4 Fragment
99.1% HPLC
CAS
77591-33-4
MW
4963.4 g/mol
Formula
C₂₁₂H₃₅₀N₅₆O₇₈S
Storage
−20°C / Lyophilized
G-actin sequestration Endothelial regeneration Cell migration

Synthetic fragment of the 43-amino-acid Thymosin β-4, abundant in platelets and wound tissue. Sequesters G-actin monomers via its LKKTET motif, regulating cytoskeletal dynamics. Promotes cell migration in scratch-wound assays via PI3K/Akt signaling.

UPC-005
Epitalon
Pineal Tetrapeptide
99.5% HPLC
CAS
307297-39-8
MW
390.35 g/mol
Formula
C₁₄H₂₂N₄O₉
Storage
−20°C / Lyophilized
Telomerase activity Pineal / melatonin axis Circadian regulation

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal secretion Epithalamin. In vitro studies report activation of telomerase reverse transcriptase (hTERT) in somatic cells. Also studied for regulation of melatonin biosynthesis via modulation of pinealocyte activity.

UPC-006
NAD⁺
Nicotinamide Adenine Dinucleotide
99.8% HPLC
CAS
53-84-9
MW
663.43 g/mol
Formula
C₂₁H₂₇N₇O₁₄P₂
Storage
−20°C / Lyophilized
Sirtuin activation Mitochondrial NAD⁺ pool DNA repair via PARPs

Coenzyme in hundreds of redox reactions, cycling between NAD⁺ (oxidized) and NADH (reduced) forms. Also a direct substrate for sirtuins and poly(ADP-ribose) polymerases (PARPs), linking it to chromatin regulation and DNA damage response. Intracellular NAD⁺ levels decline measurably with age and metabolic stress.

UPC-007
Semax
ACTH(4-7) Analog
99.3% HPLC
CAS
80714-61-0
MW
870.99 g/mol
Formula
C₃₉H₅₄N₁₀O₁₁S
Storage
−20°C / Lyophilized
BDNF expression Hippocampal neurogenesis Dopaminergic modulation

Heptapeptide derived from the 4–10 sequence of ACTH, with a Pro-Gly-Pro C-terminal extension that confers enzymatic stability. Research in rodent models demonstrates dose-dependent increase in BDNF mRNA in hippocampal tissue and modulation of the BDNF/TrkB signaling axis. Currently out of stock — join the waitlist.

UPC-008
MOTS-c
Mitochondrial-Derived Peptide
99.0% HPLC
CAS
1627580-64-6
MW
1820.2 g/mol
Formula
C₇₈H₁₃₃N₂₃O₂₂S₂
Storage
−20°C / Lyophilized
AMPK pathway Insulin sensitivity models Mitochondrial signaling

Sixteen-amino-acid peptide encoded within the 12S rRNA region of mitochondrial DNA — one of the first mitokines identified. Activates AMPK following one-carbon metabolic stress, affecting downstream mTOR and gluconeogenic pathways. In vivo rodent studies show improved insulin sensitivity and metabolic flexibility.

Mechanism descriptions reference peer-reviewed in vitro and pre-clinical literature. No compound is approved for human therapeutic use.

04 · Stability

Cold-chain
from lab
to door.

Peptides are chemically sensitive. Temperature excursions above −20°C promote aggregation, oxidation of cysteine residues, and deamidation of asparagine — degradation pathways that reduce functional purity without changing the visual appearance of the product. Lyophilization removes water to halt hydrolytic degradation during storage and transit. Every order ships with rated insulated packaging and gel ice calibrated to the transit window.

Bulk storage
−20°C / Dry
Form factor
Lyophilized powder
Transit packaging
Insulated + gel ice

Orders placed before 14:00 ET ship same day from our Miami facility. Delivery within Florida: 1–2 business days, maintaining cold-chain integrity throughout. All Miami-area orders ship free, with no order minimum.

05 · Reference

Defined
terms.

The vocabulary above — HPLC, COA, SPPS, RUO, 503A, 503B, API, USP <797> and <795> — is precise on purpose. Every term has a regulatory or analytical meaning that the buyer is responsible for understanding. The glossary defines each one with the framing of how it applies to a B2B account; the compound index expands each catalog entry into a full scientific profile.

Legal notice

All compounds sold by US Pept Clinic are supplied exclusively to verified B2B accounts — licensed research institutions for in vitro laboratory use, or licensed 503A compounding pharmacies as active pharmaceutical ingredients for patient-specific compounding operations. No compound is approved by the FDA for human or veterinary therapeutic use. Descriptions of biological mechanisms are drawn from published peer-reviewed literature and do not constitute medical claims. US Pept Clinic makes no representations regarding clinical efficacy or safety in humans. Purchasers assume full responsibility for compliance with applicable federal, state, and local regulations governing the purchase and use of purchased compounds.

Next step

Research compounds verified to the
same standard every time.

Apply for a company account to access pricing, place orders, and download COAs for every batch you receive.

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