Quality · Transparency

COA Archive

Every product we ship comes with a full Certificate of Analysis from an independent, accredited third-party laboratory. Not a house lab. Not self-reported. An independent party with no financial incentive to report a favorable result.

Independent Lab HPLC ≥99% Mass Spectrometry Confirmed Lot-Specific
HPLC Purity Floor
≥99%
Testing Standard
3rd Party
COA per Order
Per Lot
Verification
On-chain
Foundations

What Is a Certificate of Analysis?

A Certificate of Analysis (COA) is the primary quality document accompanying a research compound. It provides analytical evidence that the compound you received is what the label says it is, at the purity stated — and nothing more.

A COA is only meaningful when issued by an independent third-party laboratory. A document produced by the same entity that manufactured the compound has no analytical validity — it is a self-attestation, not independent verification. This distinction matters.

At US Peptide Clinic, every lot is tested by an accredited external laboratory before it is added to inventory. Products failing to meet our purity threshold are rejected — they never reach your order.

◆ COA INTEGRITY CHECK

When evaluating any peptide supplier's COA, ask these questions:

  • Who performed the testing? Is it a named, accredited third-party lab?
  • Does the batch number on the COA match the lot number printed on your vial?
  • Is the chromatogram embedded, or just a purity percentage with no data?
  • Is mass spectrometry data included confirming molecular identity?
  • Does the testing date predate your shipment date?
Methodology

How We Test

HPLC

High-Performance Liquid Chromatography

Primary purity analysis. Separates compound components under high pressure and UV detection to quantify the target peptide fraction against total peak area. All our products ship at ≥99% HPLC purity.

Output Purity percentage + chromatogram graph
MS

Mass Spectrometry

Molecular identity confirmation. Measures the exact mass-to-charge ratio of the compound to verify it matches the theoretical molecular weight of the declared peptide sequence. Confirms identity at the molecular level.

Output Observed m/z vs. theoretical m/z match
AA-SEQ

Amino Acid Sequence Verification

Confirms the correct amino acid sequence and any post-translational modifications (acetylation, amidation, pegylation, etc.). Critical for complex or modified peptides where sequence errors can occur during synthesis.

Output Confirmed sequence string with modification notation
RP-HPLC

Reverse-Phase HPLC

Secondary purity confirmation using a different column chemistry than standard HPLC. Provides an independent purity measurement and helps characterize impurity profiles — residual solvents, incomplete synthesis intermediates, and oxidation products.

Output Impurity profile + reverse-phase chromatogram
Document Anatomy

What Every COA Contains

Our COAs follow a standardized format so researchers can quickly locate the data they need. Below is every field included in a US Peptide Clinic COA, along with what that field tells you.

Field What it tells you
Product Name Full IUPAC name + common research designation
Lot / Batch Number Matches label on vial and secondary packaging
Molecular Formula Verified chemical formula
Molecular Weight Theoretical vs. observed (MS)
HPLC Purity Percentage ± measurement tolerance
Chromatogram Embedded HPLC trace with peak labels
MS Spectrum Observed ion masses confirming identity
Impurity Profile Any peaks >0.1% area identified
Testing Date Date of analysis — relevant for stability assessment
Testing Laboratory Third-party lab name, accreditation, and signature
Storage Conditions Temperature, humidity, light exposure requirements
Expiry / Retest Date Recommended retest date under stated storage conditions
Access

Your COAs, Per Order

Approved account holders can download lot-specific COAs for every order directly from their account dashboard. COAs are available immediately after your order ships.

Access My COAs Apply for Access

B2B approval required · No individual accounts

Our Position

Why independent testing is the only testing that counts

01

No conflict of interest

A third-party lab has no revenue tied to your order passing. Their incentive is methodological accuracy. Ours is reputation. That alignment produces reliable data.

02

Research reproducibility

Reproducibility failure in peptide research frequently traces back to compound impurity. A COA with a real chromatogram lets researchers assess baseline purity as a variable in their study design.

03

Regulatory defensibility

In an environment of increasing FDA and state-level scrutiny, documented lot-specific testing is a material component of a compliant research compound program. We keep your records complete.